Cannabinoid are compounds that occur naturally and interact with receptors located throughout the body to attain specific psychological effects. Over 100 different cannabinoid can be found in the cannabis plant. Delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) are the most commonly utilized. Endocannabinoids are neurotransmitters that bind to receptors and affect pain perception, appetite, mood, and sleep. Exogenous cannabinoid are not produced by the body but can be found in cannabis compounds such as CBD and THC. THC interacts with parts of the body that get you high, whereas CBD interacts with your body’s details that reduce inflammation. Research has identified cannabinoid 1 receptors and cannabinoid 2 receptors that respond to cannabis. CB1 receptors are more in the central nervous system, whereas CB2 is prominent in the peripheral nervous system. THC has a high propensity for CB1 receptors, whereas CBD has a high affinity for CB2 receptors.
Key Differences between CBD and THC
The recent legalization of cannabis and its products has led to an increase in its demand. Consumers are starting to explore available options regarding cannabis use. Cannabidiol can be obtained from cannabis or hemp. Both of them are obtained from the cannabis sativa plant. CBD and THC have a similar chemical structure. They both interact with the same cannabinoid receptors. However, they differ in their psychoactive effects. CBD possesses psychoactive properties but not in the THC manner. CBD doesn’t give the high associated with THC. Research has demonstrated that CBD helps with depression, seizures, and anxiety. In the brain, THC binds with cannabinoid 1 receptors. It produces euphoric effects or high. Cannabidiol binds weakly to cannabinoid receptors. Cannabidiol requires THC to bind to cannabinoid 1 receptors. Additionally, it aids in reducing some of THC’s undesirable psychoactive effects such as sedation or euphoria.
In terms of medical benefits, both CBD and THC have more or less the same benefits. The only difference is that CBD lacks the euphoric effects associated with THC. CBD is well tolerated even in large doses.
Previous research suggests that any adverse reactions that occur with cannabis use are likely to be attributed to drug-to-drug interactions between CBD and other drugs. THC causes transient effects such as tachycardia, coordination problems, dry mouth, diminished reaction times, anxiety, and memory loss. Research has associated high THC use with long-term adverse psychiatric effects. Especially for adolescents whose THC consumption is high. Although, no conclusive evidence has proved that high THC use can cause psychiatric disorders like schizophrenia. There is no risk of addiction associated with CBD. No research has demonstrated that often or too much CBD use can cause dependency. However, since CBD consumption has increased, it’s only a matter of time and more research. On the other hand, THC can be addicting. Approximately 30% of regular THC users experience marijuana use disorder.
Legalization of CBD & THC
Laws related to cannabis in the United States are evolving regularly. Under federal law, CBD is still regarded as a schedule 1 drug. Several states have also passed cannabis-related laws. Medical cannabis with high levels of THC has been legalized. Close to 33 states, including Washington DC, have legalized recreational use of THC and CBD. Among the controlled substances, CBD has been removed, whereas THC remains. Therefore, there’s a need for additional research and reasonable regulation. Rescheduling cannabis to schedule 2 or 3 would open up more research opportunities. In cookies, lotions, or dark chocolates, the amount of CBD is very low compared to what would be required to achieve therapeutic doses. 5-10 milligrams of oral THC are enough to achieve the desired effect. CBD would require thousands or hundreds of milligrams. CBD products are now a part of many people’s health and wellness. These habits encourage better sleep, deep feelings of focus, and contribute to the overall balance.
Cannabis became legal in Canada back on October 17, 2018, and since then, legal cannabis has become more and more accessible across the country. Adults in every province and territory now have access to legal marijuana products like strains, edibles, vape pens, concentrates, and oils, available in both physical stores and online.
When you have to consume large volumes of a drug to achieve therapeutic effects, the risk of contamination is high. THC doesn’t need highly concentrated products. The challenge of contamination would be less. To conclude, a high THC content has long been prized by cannabis consumers. The potency of a drug is a determining factor in consumer choices. High potency makes particular strains more desirable. The surge in THC demand has led to an oversaturation of high-potency products. Consumers are now shifting towards less intense products which are lower in THC and higher in CBD. CBD has no lethal dose or known serious side effects. Also, high doses of CBD often produce a profoundly relaxing experience.